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蔡振东

发布时间:2020/06/16 15:02 作者: 点击量:

    

姓    名:蔡振东

工作单位:宁波大学 食品与药学学院

通信地址:宁波梅山保税港区七星南路169号国际楼701室

联系方式:caizhendong@nbu.edu.cn;13586701099

研究方向:乳酸菌功能基因;益生菌与肠道稳态;功能性发酵乳;畜产品掺伪分子诊断



个人简介:

微生物学博士,硕士生导师。主要从事病原真菌的致病机理、益生细菌分子功能及应用研究,发表论文30余篇、以第一作者/通讯作者在mSphere, Cell Microbiol, Front Microbiol, Front Nutr, J Funct Foods, Poultry Sci等主流SCI期刊发表16篇SCI论文。主持国家、省、市厅级项目8项,参与国家自然科学基金重点和面上等省部级以上项目多项。授权发明专利2项,科技成果转化1项,在申发明专利4项。指导学生获得国家级大学生创新创业训练计划项目,浙江省新苗人才计划,研究生科研创新基金重点和一般项目等。担任Front Microbiol,Front Immunol和Front Cell Infect Mi期刊编委。


主持科研项目:

(1) 国家自然科学基金:脂磷壁酸合酶LtaS介导的植物乳杆菌黏附效应及其机制研究(31901668);

(2) 浙江省自然科学基金:脂磷壁酸介导植物乳杆菌肠道定殖的功能解析(LY22C200002);

(3) 光明乳业股份有限公司乳业生物技术国家重点实验室开放基金:群体感应系统调控乳酸菌协同发酵的功能研究(SKLDB2022-005);

(4) 宁波市自然科学基金:LuxS/AI-2群体感应系统介导的植物乳杆菌发酵乳品质及机制研究(2021J108);

(5) 宁波市自然科学基金:细胞壁脂磷壁酸合酶介导植物乳杆菌的细胞黏附效应(2019A610436);

(6) 北京市开放基金:LuxS/AI-2群体感应系统介导益生乳酸菌发酵乳风味特征及其形成机制研究(SPFW2020YB13);

(7) 中国博士后基金:烟曲霉高铜响应转录因子AceA调控铜解毒机制和毒力研究(2016M591876)。


代表论文:

[1] Zhou S, Zhong G, Zhou H, Zhang XX, Zeng XQ, Wu Z, Pan DD*, He J*, Cai ZD*, Liu Q, A Heptaplex PCR Assay for Molecular Traceability of species Origin With High Efficiency and Practicality in Both Raw and Heat Processing Meat Materials. Front Nutr, 2022, 9:890537.

[2] Lu QQ, Guo YQ, Yang G, Cui L, Wu Z, Zeng X, Pan DD, Cai ZD*, Structure and Anti-Inflammation Potential of Lipoteichoic Acids Isolated from Lactobacillus Strains. Foods, 2022, 11(11)

[3] Cai ZD, Zhong GW, Liu QQ, Yang XQ, Zhang XX, Zhou S, Zeng XQ, Wu Z, Pan DD*, Molecular Authentication of Twelve Meat Species Through a Promising Two-Tube Hexaplex Polymerase Chain Reaction Technique. Front Nutr, 2022, 9

[4] Yang CY, Zhong GW, Zhou S, Guo YQ, Pan DD, Wang S*, Liu QQ, Xia Q, Cai ZD*. Detection and characterization of meat adulteration in various types of meat products by using a high-efficiency multiplex polymerase chain reaction technique. Front Nutr, DOI:10.3389/fnut.2022.979977.

[5] Wang S, Yuan A, Zeng L, Hou S, Wang M, Li L, Cai ZD*, Zhong GW, The putative polysaccharide synthase AfCps1 regulates Aspergillus fumigatus morphogenesis and conidia immune response in mouse bone marrow-derived macrophages. J Microbiol, 2021, 59:1-12.

[6] Cai ZD, Zhou S, Liu QQ, Ma H, Yuan XY, Gao JQ, Cao JX, Pan DD*, A Simple and Reliable Single Tube Septuple PCR Assay for Simultaneous Identification of Seven Meat Species. Foods, 2021, 10(5):1083.

[7] Cai ZD, Wang PY, Guo YX, Zeng XQ, Wu Z, Pan DD*, S-layer protein modulates the stimulatory effects of Lactobacillus acidophilus CICC 6074 by triggering PKC signaling cascade in RAW 264.7 cells. J Funct Foods, 2020, 67:103841.

[9] Cai ZD, Ruan YF, He J, Dang YL, Cao JX, Sun YY, Pan DD*, Tian HW, Effects of microbial fermentation on the flavor of cured duck legs. Poultry Sci, 2020, 99(9):4642-4652.

[9] Cai ZD, Du W, Liu L, Pan DD, Lu L*, Molecular characteristics of the conserved Aspergillus nidulans transcription factor Mac1 and its functions in response to copper starvation. mSphere, 2019, 4(1):e00670-00618.

[10] Cai ZD, Xu PX, Wu Z, Pan DD*, Anti-inflammatory activity of surface layer protein SlpA of Lactobacillus acidophilus CICC 6074 in LPS-induced RAW 264.7 cells and DSS-induced mice colitis. J Funct Foods, 2018, 51:16-27.

[11] Cai ZD*, Du WL, Zhang Z, Guan LY, Zeng QQ, Chai YF, Dai CC, Lu L*, The Aspergillus fumigatus transcription factor AceA is involved not only in Cu but also in Zn detoxification through regulating transporters CrpA and ZrcA. Cell Microbiol, 2018, 20(10):e12864.

[12] Cai ZD, Du WL, Zeng QQ, Long NB, Dai CC, Lu L*, Cu-sensing transcription factor Mac1 coordinates with the Ctr transporter family to regulate Cu acquisition and virulence in Aspergillus fumigatus. Fungal Genet Biol, 2017, 107:31-43.

[13] Cai ZD, Chail YF, Zhang CY, Fengl RY, Sang H, Lu L*, Molecular Characterization of Gβ-Like Protein CpcB Involved in Antifungal Drug Susceptibility and Virulence in A. fumigatus. Front Microbiol, 2016, 7:106.

[14] Cai ZD, Chai YF, Zhang CY, Qiao WR, Sang H, Lu L*, The Gβ-like protein CpcB is required for hyphal growth, conidiophore morphology and pathogenicity in Aspergillus fumigatus. Fungal Genet Biol, 2015, 81:120-131.


授权发明专利:

(1)一种用于同时鉴别7种肉源食品的PCR检测用引物组和方法,专利号:ZL202110433969.8。已转化


讲授课程:

《微生物学与免疫学》,《微生物学与免疫学实验》,《数理软件统计分析》,《海洋生物与人类生活》。


所属学科及招生专业:

食品科学与工程;生物与医药;食品加工与安全。


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